In this first ever study (2015) to evaluate the effect of acupuncture on endometrial receptivity in women undergoing Frozen Embryo Transfer, results indicate significant effect in producing higher rates of embryo implantation, clinical pregnancy and live birth following IVF/ART.
Shuai et al ran a single-blind, prospective randomised controlled trial with a total of 68 women undergoing frozen embryo transfer (FET). A higher frequency of the ultrasonographic triple-line endometrial pattern, greater endometrial/subendometrial VI and increased HOXA10 protein expression were noted in the acupuncture group in the present study.
Women with a regular menstrual cycle could be offered electro-acupuncture in the 3 months prior to FET as acupuncture appears to enhance endometrial receptivity. Further research is required to confirm the apparent benefits of acupuncture in women undergoing FET, ideally in the form of large-scale multicentre clinical trials.
Source: Zhenhong Shuai, Fang Lian, Pengfei Li, Wenxiu Yang. Effect of transcutaneous electrical acupuncture point stimulation on endometrial receptivity in women undergoing frozen-thawed embryo transfer: a single-blind prospective randomised controlled trial. Acupunct Med 2015;33:9–15.